Joint Meeting of ISBRA and ESBRA 2022

PROGRAM

S0 - FREE ORAL COMMUNICATIONS 1

Room A

Local Time: 14:00 - 15:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Consuelo Guerri

Spain

Wolfgang Sommer

Germany

Learning and synaptic plasticity impairments after the first binge drinking episodes in adolescent rats are due to neuroinflammation effects through epigenetic mechanisms

14:00 - 15:30


Chloé Deschamps

France

Impact of alcohol consumption on epigenetic age in diverse populations

14:00 - 15:30


Ke Xu

USA

Observational and genetic associations of alcohol consumption with 1500 circulating protein biomarkers

14:00 - 15:30


Pek Kei Im

UK

Characterizing the transcriptional fingerprint of neuronal ensembles underlying alcohol memories

14:00 - 15:30


Segev Barak

Israel

S01 - FREE ORAL COMMUNICATIONS 2

Room B

Local Time: 14:00 - 15:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Jonathan Chick

UK

Andrzej Jakubczyk

Poland

Direct comparison of brain volumes within the Papez’s circuit in Alzheimer disease and Korsakoff's syndrome

14:00 - 15:30


Anne Lise Pitel

France

A volumetric exploration of insula in Alcohol Use Disorder and Korsakoff’s syndrome: let’s go back to basics

14:00 - 15:30


Anne Lise Pitel

France

Neurofunctional domains factors from the addictions neuroclinical assessment mediate the relationship between childhood trauma and alcohol use outcomes

14:00 - 15:30


Tommy Gunawan

USA

Addiction therapeutic communities residents' neuropsychological functioning at entry

14:00 - 15:30


Simon Deniel

France

An eye-tracking exploration of the alcohol-related attentional bias in severe alcohol use disorder: influence of subjective craving and cognitive load

14:00 - 15:30


Pierre Maurage

Belgium

S02 - FREE ORAL COMMUNICATIONS 3

Room C

Local Time: 14:00 - 15:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Sophie Leclercq

Belgium

Maciej Kopera

Poland

Tackling heterogeneity: individual variability of emotion decoding deficits in severe Alcohol Use Disorder

14:00 - 15:30


Pierre Maurage

Belgium

Leukocyte mitochondrial DNA copy number and telomere length in alcohol-dependent patients; association with socio-demographic and health characteristics

14:00 - 15:30


Teodora Taseva

Bulgaria

Future diagnosis of alcohol-related disease is associated with alterations in the serum metabolite profile

14:00 - 15:30


Olli Kärkkäinen

Finland

Alcohol intake and cause-specific mortality: conventional and genetic evidence in 500,000 men and women in China

14:00 - 15:30


Iona Millwood

UK

Binge drinking during adolescence: microbiome, immune and cognitive alterations

14:00 - 15:30


Carina Carbia

Ireland

Coffee Break

Room E

Local Time: 15:30 - 16:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

PLENARY LECTURE

The synaptic role of the stress system and cytokines in Alcohol Use Disorder

Room A

Local Time: 16:00 - 17:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chair:
Markus Heilig

Sweden

Keynote Speaker:
Marisa Roberto

USA

Opening Ceremony

Room A

Local Time: 17:00 - 18:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

GET TOGETHER PARTY

Room E

Local Time: 18:00 - 19:00 CEST (GMT+2 Warsaw)

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S03 - Genetic polymorphism of alcohol metabolizing enzyme (ALDH2) in alcoholism

Room A

Local Time: 08:30 - 10:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Sung-Gon Kim

South Korea

Mikko Salaspuro

Finland

Comparison study on the blood acetaldehyde concentration according to ALDH2 genotype and age

08:30 - 10:00


Sung-Young Huh

South Korea

Identification on risk factors for Alcohol Use Disorders using the alcoholics with inactive ALDH model (AIA model)

08:30 - 10:00


Mitsuru Itoh

Japan

Acetaldehyde modulates the alcohol responses in subjects with variant ALDH2*2 gene allele

08:30 - 10:00


Yi-Chyan Chen

Taiwan

ALDH2-deficiency: unique human cancer model for acetaldehyde based on Mendelian randomization

08:30 - 10:00


Mikko Salaspuro

Finland

S04 - Non-invasive brain-stimulation approaches to the treatment of alcohol addiction

Room B

Local Time: 08:30 - 10:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Markus Heilig

Sweden

Wolfgang Sommer

Germany

Network analysis of brain activity in AUD patients and rats: Implications for therapy development

08:30 - 08:45


Wolfgang Sommer

Germany

Deep repetitive transcranial magnetic stimulation for alcohol dependence: targeting insula or medial prefrontal/anterior cingulate cortex

08:45 - 09:00


Markus Heilig

Sweden

Medial prefrontal cortex theta burst stimulation improves treatment outcomes in Alcohol Use Disorder: a double blind, sham-controlled neuroimaging study

09:00 - 09:15


Colleen Hanlon

USA

Accelerated rTMS in alcohol addiction

09:30 - 10:00


Chris Baeken

Belgium

S05 - Mechanistic and clinical aspects of portal hypertension in alcohol liver disease

Room C

Local Time: 08:30 - 10:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Michał Kukla

Poland

Sebastian Mueller

Germany

Spleen stiffness to liver stiffness ratio in ALD and prognostic implications

08:30 - 10:00


Omar Elshaarawy

UK

Histological features of alcohol-related liver disease and portal hypertension

08:30 - 10:00


Karoline Lackner

Austria

Frailty and sarcopenia in alcoholic liver disease

08:30 - 10:00


Michał Kukla

Poland

The sinusoidal pressure hypothesis to explain portal hypertension in alcohol-related liver disease

08:30 - 10:00


Sebastian Mueller

Germany

Diagnosis and treatment of alcoholic hepatitis

08:30 - 10:00


Ivica Grgurevic

Croatia

PLENARY LECTURE

The gut microbiome as a disease driver and therapeutic target in alcohol-associated liver disease

Room A

Local Time: 10:00 - 11:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chair:
Shilpa Chokshi

UK

Keynote Speaker:
Bernd Schnabl

USA

Coffee Break

Room E

Local Time: 11:00 - 11:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

S06 - Molecular mechanisms of the individual vulnerability to develop compulsive alcohol seeking and taking: evidence from preclinical research

Room A

Local Time: 11:15 - 12:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
David Belin

UK

Esi Domi

Sweden

Sex differences in pathological choice of alcohol over a healthy reward

11:15 - 12:45


Eric Augier

Sweden

Baclofen decreases compulsive alcohol drinking in rats through a PKCδ-mediated mechanism in the central amygdala

11:15 - 12:45


Esi Domi

Sweden

Alcohol use as a coping strategy increases the vulnerability to develop compulsive drinking

11:15 - 12:45


Lucia Marti-Prats

UK

Alcohol versus social reward: testing the effect of social reward on choice for alcohol in rats

11:15 - 12:45


Nathan Marchant

Netherlands

S07 - Emotional and cognitive processing and their predictive value for heavy alcohol drinking

Room B

Local Time: 11:15 - 12:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Aleksandra Herman

Poland

Maciej Kopera

Poland

Suppressing alcohol memories: functional connectivity patterns in young binge drinkers

11:15 - 12:45


Natália Almeida Antunes

Portugal

Emotional and cognitive processing and their predictive value for heavy alcohol drinking

11:15 - 12:45


Kyriaki Nikolaou

UK

Bodily confusion: the differentiation between emotional and physiological states in student alcohol users - preliminary results

11:15 - 12:45


Aleksandra Herman

Poland

Neural correlates of cognitive and affective theory of mind in adults with a family history of Alcohol Use Disorder: a vulnerability factor?

11:15 - 12:45


Franca Schmid

France

S08 - Pathophysiology, regeneration and clinical management of severe alcoholic hepatitis

Room C

Local Time: 11:15 - 12:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Steven Dooley

Germany

Sebastian Mueller

Germany

Pathophysiology of severe alcohol related hepatitis - the organ response with damage, inflammation and scarring

11:15 - 12:45


Shilpa Chokshi

UK

How can a patient survive from acute liver failure?

11:15 - 12:45


Hong-Lei Weng

Germany

Systemic inflammation and utilization of comprehensive proteome resources in alcohol associated liver disease

11:15 - 12:45


Robert Schierwagen

Germany

Newest developments in clinical management of severe alcoholic hepatitis

11:15 - 12:45


Alexandre Louvet

France

Lunch break and Poster Session

Room E

Local Time: 12:45 - 14:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

S09 - Neuroimmune signaling and Alcohol Use Disorders

Room A

Local Time: 14:00 - 15:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Fulton Crews

USA

Antonio Noronha

USA

How does neuroimmune signaling impact AUD?

14:00 - 15:30


Consuelo Guerri

Spain

The gut microbiota, IL8, craving and sociability in AUD

14:00 - 15:30


Philippe de Timary

Belgium

Microglia, TLR7 and extracellular vesicles as potential therapeutic targets for AUD pathology

14:00 - 15:30


Leon Coleman

USA

The endogenous neurosteroid [3α,5α]3 hydroxypregnan-20-One (3α,5α-THP, allopregnanolone) inhibits toll-like receptor (TLR) Inflammatory signaling with relevance to alcohol use disorders

14:00 - 15:30


A. Leslie Morrow

USA

S10 - Genetically-based strategies for the prevention of alcohol related problems

Room B

Local Time: 14:00 - 15:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Marc Schuckit

USA

Helmut Seitz

Germany

Inhibition of cytochrome P4502E1 improves alcoholic liver disease: a possible strategy for intervention

14:00 - 15:30


Helmut Seitz

Germany

Univenture: feasibility of a developmentally-adapted, evidence-based drug and alcohol preventure program for university students

14:00 - 15:30


Patricia Conrod

Canada

Development of a personalized feedback program for college students targeting genetically influenced externalizing and internalizing characteristics

14:00 - 15:30


Danielle Dick

USA

Mitigating the risk for alcohol problems associated with the genetically influenced low level of response to alcohol: an expanded protocol

14:00 - 15:30


Marc Schuckit

USA

S11 - Identification of new pathogenically important therapeutic targets for alcohol-associated liver disease (ALD) prevention

Room C

Local Time: 14:00 - 15:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Natalia Osna

USA

Kusum Kharbanda

USA

Enhanced red blood cell turnover/erythrophagocytosis as novel important progression factor of alcoholic liver disease

14:00 - 15:30


Sebastian Mueller

Germany

Clinical and preclinical studies identify phosphodiesterase 4 as a potential therapeutic target for ALD

14:00 - 15:30


Leila Gobejishvili

USA

Developing immunomodulatory therapies for alcohol-related liver disease (ALD)

14:00 - 15:30


Shilpa Chokshi

UK

Role of alcohol on HBV core peptide-MHC class I complex presentation in hepatocytes of HBV-infected humanized mice

14:00 - 15:30


Murali Ganesan

USA

PLENARY LECTURE

Genetics and pharmacogenetics of Alcohol Use Disorder

Room A

Local Time: 15:30 - 16:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chair:
Jennifer Thomas

USA

Keynote Speaker:
Henry Kranzler

USA

Coffee Break

Room E

Local Time: 16:30 - 16:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

S12 - Neurogenomics of alcohol: Molecular signatures of cellular processes in AUD models

Room A

Local Time: 16:45 - 18:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Igor Ponomarev

USA

Dayne Mayfield

USA

Cell-type specific gene expression changes in the mouse prefrontal cortex after chronic ethanol drinking

16:45 - 18:15


Igor Ponomarev

USA

Spatial transcriptomics and SNRNA sequencing identify spatially resolved overlapping prefrontal cortex cell-type specific mechanism between alcohol dependence and immune activation mouse models

16:45 - 18:15


Nihal Salem

USA

Gene expression signatures in AUD - a translational approach

16:45 - 18:15


Marion Friske

Germany

Transcriptomic changes in PKCd neurons associated with punishment-resistant alcohol self-administration in rats

16:45 - 18:15


Estelle Barbier

Sweden

S13 - Intersection of pain and Alcohol Use Disorder risk

Room B

Local Time: 16:45 - 18:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Scott Edwards

USA

Marcin Wojnar

Poland

Analgesic efficacy of alcohol in the context of chronic pain

16:45 - 18:15


Scott Edwards

USA

Physical pain and recovery from Alcohol Use Disorder

16:45 - 18:15


Katie Witkiewitz

USA

Pain and emotion dysregulation in Alcohol Use Disorder

16:45 - 18:15


Andrzej Jakubczyk

Poland

Emerging adulthood as a critical developmental period for pain, risky drinking and alcohol-related problems

16:45 - 18:15


Emily Zale

USA

S14 - The first ISBRA-ESBRA Charles Lieber symposium: alcohol, cannabis, opioids, microbiome and chronic diseases

Room C

Local Time: 16:45 - 19:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Manuela Neuman

Canada

Helmut Seitz

Germany

Introduction

16:45 - 17:00


Helmut Seitz

Germany

From alcoholism to rehabilitation - the realities of oral cancer

16:45 - 18:15


Eszter Somogyi-Ganss

Canada

Coronavirus SARS-CoV-2 and alcoholic and metabolic liver diseases

16:45 - 18:15


Stephen D.H Malnick

Israel

Personalized non-invasive biomarkers useful in differential diagnosis of alcohol-induced dementia and Alzheimer's disease dementia

16:45 - 18:15


Manuela Neuman

Canada


Edward Lichten

USA

Alcohol and phosphatidylethanolamine methyltransferase deficiency

16:45 - 18:15


Kusum Kharbanda

USA

Impact of alcohol consumption on genetic liver diseases - or the other way around

16:45 - 18:15


Peter Ferenci

Austria

Methemoglobinemia: nature, forensic implications and diagnostic and analytical challenges

18:15 - 19:45


Federick Hellman

USA

A Novel Chemical Entity for Treatment of Alcohol Use Disorder

18:15 - 19:45


Paula Hoffman

USA

Interaction between opioids, alcohol, cannabis and therapeutics: apoptosome, inflammasome

18:15 - 19:45


Manuela Neuman

Canada

S15 - Oxytocin for the treatment of alcohol addiction – a cross-species view

Room A

Local Time: 18:15 - 19:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Rainer Spanagel

Germany

Mary Lee

USA

Evidence of central signaling after systemic administration of oxytocin

18:15 - 19:45


Mary Lee

USA

Targeting the oxytocin system in rats

18:15 - 19:45


Marcus Meinhardt

Germany

Oxytocin reduces alcohol drinking and stress-induced relapse-like behavior via signalling at central oxytocin receptors in mice

18:15 - 19:45


Howard Becker

USA

Targeting the OXT system in prairie vole

18:15 - 19:45


Andrey Ryabinin

USA

S16 - Alcohol and socio-affective information processing

Room B

Local Time: 18:15 - 19:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Pierre Maurage

Belgium

Sara Jo Nixon

USA

Acute effects of alcohol on social decision making

18:15 - 19:45


Irene Perini

Sweden

Emotional memory bias in binge drinking women

18:15 - 19:45


Carina Carbia

Ireland

Socio-affective attentional biases in severe Alcohol Use Disorder: an eye-tracking study

18:15 - 19:45


Arthur Pabst

Belgium

The impact of emotional stimuli on working memory in severe Alcohol Use Disorder

18:15 - 19:45


Ben Lewis

USA

S17 - Biomarkers and new targets in Alcohol Use Disorders: translational approaches

Room A

Local Time: 08:15 - 09:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Mickael Naassila

France

Philippe de Timary

Belgium

Plasmatic biomarkers of brain suffering during alcohol withdrawal in humans

08:15 - 09:45


Florence Vorspan

France

Subthamalic nucleus deep brain stimulation reduces alcohol intake in rats under influence of proximal social factors

08:15 - 09:45


Christelle Baunez

France

Role of GPR88 in ethanol drinking: a new pharmacological target

08:15 - 09:45


Sami Ben Hamida

France

Mutant mice expressing gene variants of α5 nicotinic receptors as preclinical models Cloninger typology for Alcohol Use Disorders

08:15 - 09:45


Vincent David

France

S18 - Interoception: implications for substance and alcohol use

Room B

Local Time: 08:15 - 09:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Pierre Maurage

Belgium

Mateo Leganes-Fonteneau

USA

“Inside” and “Insight”: measuring interoception and meta-cognition in drug addiction

08:15 - 09:45


Martin Paulus

USA

Interoceptive correlates of acute alcohol administration and future clinical avenues

08:15 - 09:45


Mateo Leganes-Fonteneau

USA

The body of emotion - interoception and emotions processing in individuals with Alcohol Use Disorder

08:15 - 09:45


Paweł Wiśniewski

Poland

Measuring interoception in Alcohol-Use Disorders: current tools and ways forward

08:15 - 09:45


Olivier Desmedt

Belgium

S19 - ESBRA-JMSAAS joint symposium

Mechanisms of alcohol-mediated liver injury

Room C

Local Time: 08:15 - 09:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Kenichi Ikejima

Japan

Sebastian Mueller

Germany

Role of gut-liver axis and innate immunity in the pathogenesis of alcohol-related liver disease

08:15 - 09:45


Akira Uchiyama

Japan

The role of disease mediators in alcohol-related liver diseases

08:15 - 09:45


Akiko Eguchi

Japan

Alcohol-related hepatotoxicity and mitochondria: can we consider ALD as a mitochondrial disorder?

08:15 - 09:45


Elena Palma

UK

Signatures of acute-on-chronic liver failure in Abcb-4KO mice upon acute chemical intoxication

08:15 - 09:45


Seddik Hammad

Germany

PLENARY LECTURE

ISBRA Tabakoff Award Plenary Lecture

Implication of inactive ALDH2 on alcohol consumption, intoxication and related harms, and other disorders

Room A

Local Time: 09:45 - 10:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chair:
Sung-Gon Kim

South Korea

Keynote Speaker:
Susumu Higuchi

Japan

Coffee Break

Room E

Local Time: 10:45 - 11:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

S20 - Translational neuroimaging of alcohol addiction: towards consilience of structural and functional MRI findings from human and animal models

Room A

Local Time: 11:00 - 12:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Wolfgang Sommer

Germany

Corinde Wiers

USA

Altered diffusivity in the alcoholic brain

11:00 - 12:30


Santiago Canals

Spain

Structural and functional signatures of chronic alcohol effects in mice

11:00 - 12:30


Laura Adela Harsan

France

The brain’s functional connectivity backbone and the impact of AUD

11:00 - 12:30


Maria Ercsey-Ravasz

Romania

Effects of a single-dose ketone ester on alcohol consumption and brain glucose metabolism in rats and humans

11:00 - 12:30


Corinde Wiers

USA

S21 - EUFAS-ESBRA SYMPOSIUM

Innovative pharmacological approaches for treating Alcohol Use Disorder

Room B

Local Time: 11:00 - 12:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Jørgen Bramness

Norway

Marcin Wojnar

Poland

Investigating new neuroendocrine target toward the development of new pharmacotherapies for Alcohol Use Disorder

11:00 - 12:30


Lorenzo Leggio

USA

Efficacy of psychedelics in animal models of binge drinking and Alcohol Use Disorder

11:00 - 12:30


Mickael Naassila

France

The prospects of cannabidiol in Alcohol Use Disorder

11:00 - 12:30


Benjamin Rolland

France

S22 - Recent advances in the understanding of molecular mechanisms of alcohol-related liver damage

Room C

Local Time: 11:00 - 12:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Ina Bergheim

Austria

Kenichi Ikejima

Japan

Hypoxia signaling and role in alcoholic liver disease

11:00 - 12:30


Jose Fernandez-Checa

Spain

Fibrosis resolution involves more than collagen; key role of MMP-12 in fibrosis recovery

11:00 - 12:30


Toshifumi Sato

Japan

Xanthohumol ameliorates acute alcohol-induced liver injury

11:00 - 12:30


Claus Hellerbrand

Germany

MAFLD, NAFLD or ALD – how alcohol markers can help us to make a diagnosis

11:00 - 12:30


Katharina Staufer

Austria

PLENARY LECTURE

ISBRA Tabakoff Award Plenary Lecture

Cytochrome P4502E1 and alcoholic liver disease: a success story from bench to bedside

Room A

Local Time: 12:30 - 13:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chair:
Rainer Spanagel

Germany

Keynote Speaker:
Helmut Seitz

Germany

Lunch break and Poster Session

Room E

Local Time: 13:30 - 14:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

S23 - Interdisciplinary studies of ethanol drinking: from neuroinflammation to excitability

Room A

Local Time: 14:45 - 16:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Rosana Camarini

Brazil

Maria Pascual

Spain

Changes in the microbiome and intestinal dysfunctions in mice with chronic alcohol intake: role of TLR4 response

14:45 - 16:45


Maria Pascual

Spain

The activation of ALDH2 as a pharmacological strategy for treating alcohol and nicotine use disorder

14:45 - 16:15


Mario Rivera-Meza

Chile

Long-term effects of maternal separation on alcohol intake and underlying mechanisms

14:45 - 16:45


Fabio Cruz

Brazil

Glycine receptors in the nucleus accumbens and their role in ethanol effects

14:45 - 16:15


Luis Aguayo

Chile

S24 - Subgroups of alcohol dependence - useful for basic and clinical research

Room B

Local Time: 14:45 - 16:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Michie Hesselbrock

USA

Henriette Walter

Austria

Alcohol metabolizing gene subtypes and clinical characteristics of Japanese AUD patients

14:45 - 16:15


Sachio Matsushita

Japan


Susumu Higuchi

Japan

Till death do us part - AUD typology and mortality - results from two longitudinal studies

14:45 - 16:45


Victor Hesselbrock

USA

Subgroups of alcohol dependence: Lesch typology, a useful instrument for basic research?

14:45 - 16:45


Otto-Michael Lesch

Austria

Medication effects and placebo responses in subgroups of alcohol dependence

14:45 - 16:15


Henriette Walter

Austria

S25 - Bacterial infections in alcohol-related liver disease

Room C

Local Time: 14:45 - 16:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Shilpa Chokshi

UK

Antonio Riva

UK

Epidemiology and clinical consequences of bacterial infection in alcohol-related liver disease

14:45 - 16:15


Salvatore Piano

Italy

Role of the gut microbiota in alcohol-related liver disease

14:45 - 16:45


Ali Keshavarzian

USA

The intestinal virome as a new therapeutic target in alcohol-related liver disease

14:45 - 16:15


Bernd Schnabl

USA

Immunomodulatory strategies for ALD – why, how and when?

14:45 - 16:15


Antonio Riva

UK

PLENARY LECTURE

25 years of ups and downs in preclinical treatment development for alcohol relapse

Room A

Local Time: 16:15 - 17:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chair:
Mickael Naassila

France

Keynote Speaker:
Rainer Spanagel

Germany

Coffee Break

Room E

Local Time: 17:15 - 17:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

S26 - Alcohol effects on the developing brain: Festsymposium for Consuelo Guerri

Room A

Local Time: 17:30 - 19:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Maria Pascual

Spain

Rosana Camarini

Brazil

Consuelo Guerri: her contributions to the global issue of fetal alcohol spectrum disorders

17:30 - 19:00


Edward Riley

USA

Developmental alcohol exposure-induced changes in astrocyte translation in vivo

17:30 - 19:00


Marina Guizzetti

USA

Adolescence and persistent ethanol induction of TLR receptors

17:30 - 19:00


Fulton Crews

USA

Great advances on binge drinking thanks to the binge drinking model of Consuelo Guerri's research group

17:30 - 19:00


Mickael Naassila

France

S27 - Ghrelin and related peptides: novel therapeutic targets for Alcohol Use Disorder and liver injury

Room B

Local Time: 17:30 - 19:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Karuna Rasineni

USA

Kusum Kharbanda

USA

Effect of acute desacyl ghrelin administration on eating and addictive behaviours: the gut hormone in addiction study

17:30 - 19:00


Tony Goldstone

UK

Gut-brain peptides and Alcohol Use Disorder

17:30 - 19:00


Elisabet Jerlhag

Sweden

The crosstalk between alcohol use and glucagon-like peptide-1 (GLP-1) in humans and rodents: an emerging pharmacotherapeutic target?

17:30 - 19:00


Mehdi Farokhnia

USA

Role of ghrelin in modulating organ crosstalk to promote the development of alcohol-associated fatty liver disease

17:30 - 19:00


Karuna Rasineni

USA

S28 - Alcohol-associated dysbiosis; contribution to frailty comorbidities

Room C

Local Time: 17:30 - 19:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Patricia Molina

USA

Liz Simon

USA

Alcohol-induced dysbiosis and comorbidities

17:30 - 19:00


Liz Simon

USA

Bacterial toxins and inflammaging: role of TLR2 signaling cascades

17:30 - 19:00


Annette Brandt (Ina Bergheim)

Austria

Intestinal dysbiosis, alcohol and liver injury

17:30 - 19:00


Peter Starkel

Belgium

Impact of dietary intervention on social behaviour in patients with Alcohol Use Disorder

17:30 - 19:00


Sophie Leclercq

Belgium

Alcohol-associated dysbiosis in people living with HIV and geriatric syndromes and comorbidity

17:30 - 19:00


David Welsh

USA

Gala Dinner - addtional ticket required

Local Time: 20:00 - 22:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

S29 - ESBRA/ISBRA ECI Awards and the ISBRA Diversity Award Symposium

Room A

Local Time: 09:30 - 11:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Elena Palma

UK

Vijay Ramchandani

USA

Consuelo Guerri

Spain

Preclinical evidence for the therapeutic potential of biperiden on ethanol use disorders

09:30 - 09:40


Paola Palombo

Brazil

Observational and genetic associations of alcohol consumption with 1500 circulating protein biomarkers

09:40 - 09:50


Pek Kei Im

UK

Neurofunctional domains factors from the addictions neuroclinical assessment mediate the relationship between childhood trauma and alcohol use outcomes

09:50 - 10:00


Tommy Gunawan

USA

Alcohol odor recruits specific behavioral and physiological reactivity in human neonates prenatally to the drug

10:00 - 10:10


Florenzia Annunziata

Argentina

Registered reports in addiction: boosting early career research

10:10 - 10:20


Mateo Leganes-Fonteneau

USA

Gut-brain axis as a regulator of craving

10:20 - 10:30


Carina Carbia

Ireland

Introduction of ESBRA Early-career Investigator Committee

10:30 - 10:40


Elena Palma

UK

Alcoholic hepatitis: from invasive to non-invasive diagnosis

10:40 - 10:50


Adelina Horhat

Romania

Spatially resolved cell-type specific transcriptomic changes in prefrontal cortex of alcohol dependent mice

10:50 - 11:00


Nihal Salem

USA

In vitro human erythrophagocytosis model to study alcohol-mediated heme turnover

11:00 - 11:10


Cheng Chen

Germany

S30 - WHO-ISBRA SYMPOSIUM

Global status of public health approaches to alcohol, drugs and addictive behaviours and measures to counter related health harms

Room B

Local Time: 10:00 - 11:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Susumu Higuchi

Japan

Vladimir Poznyak

Switzerland

The global epidemiology of substance use and addictive behaviours and their health harms

10:00 - 11:30


Sawitri Assanangkornchai

Thailand

ICD-11 disorders due to substance use and addictive behaviours

10:00 - 11:30


John Saunders

Australia

Effective public health approaches to reduce the harmful use of alcohol

10:00 - 11:30


Thomas Babor

USA

International approaches to prevention and treatment of disorders due to addictive behaviours

10:00 - 11:30


Daniel King

Australia

S31 - Does the addition of non-invasive tests (NITs) of liver disease in alcohol services enhance early identification of significant liver disease and supplement behavioural change?

Room C

Local Time: 10:00 - 11:30 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Stephen Ryder

UK

Julia Sinclair

UK

Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD)? A feasibility randomised controlled trial

10:00 - 11:30


Mohsen Subhani

UK

Recovery narratives of people with experience of Alcohol Use Disorder who have received transient elastography

10:00 - 11:30


Stefan Rennick-Egglestone

UK

Does fibrosis screaning change alcohol consumption? Consequences of screening in 1,326 individuals at risk of alcohol-related liver disease

10:00 - 11:30


Maja Thiele

Denmark


Mohsen Subhani

UK

Developing integrated pathways for alcohol related liver disease (ArLD), how nationally implemented service level screening interventions may help

10:00 - 11:30


Julia Sinclair

UK

Coffee Break

Room E

Local Time: 11:30 - 11:45 CEST (GMT+2 Warsaw)

Your time ZONE: -

S32 - Alcohol and vesicle trafficking: role in pathogenesis and utility as biomarkers

Room A

Local Time: 11:45 - 13:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Carol Casey

USA

Laura Nagy

USA

Macrophage-derived MLKL in alcohol-associated liver disease: regulation of phagocytosis in hepatic macrophages

11:45 - 13:15


Xiaoqin Wu

USA

Increased ubiquitylation of LD proteins: role in LD degradation and hepatic fat accumulation in alcohol-induced liver disease

11:45 - 13:15


Carol Casey

USA

Blood and fecal extracellular vesicles (EVS) as biomarkers of injury in the gut-liver axis during alcohol-induced liver disease

11:45 - 13:15


Francisco Javier Cubero

Spain

Proinflammatory sphingolipid signaling in AALD

11:45 - 13:15


Harmeet Malhi

USA

S33 - FREE ORAL COMMUNICATIONS 4

Room B

Local Time: 11:45 - 13:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Pierre Maurage

Belgium

Andrzej Jakubczyk

Poland

Increased self-oriented and socially-prescribed perfectionism in severe Alcohol Use Disorder

11:45 - 13:15


Pierre Maurage

Belgium

Dimensionality of ICD-10 and ICD-11 criteria and related symptoms

11:45 - 13:15


Ulrich Preuss

Germany

Validation of a human laboratory test system to screen new medications for alcoholism (TESMA): naltrexone effects on operant alcohol- self infusion

11:45 - 13:15


Maik Spreer

Germany

Changes in drinking and smoking behavior among Korea pregnant women for the past 20 years

11:45 - 13:15


BiA Seo

South Korea

Pregnant women’s and their partners' self-reported alcohol use before and during pregnancy in a cohort of 21472 pregnancies

11:45 - 13:15


Taija Voutilainen

Finland

S34 - FREE ORAL COMMUNICATIONS 5

Room C

Local Time: 11:45 - 13:15 CEST (GMT+2 Warsaw)

Your time ZONE: -

Chairs:
Sebastian Mueller

Germany

Antonio Riva

UK

Interferon lambda 4 genetic variants are associated with bacterial infection during alcohol-related liver disease

11:45 - 13:15


Antonio Riva

UK

Mortality from alcoholic hepatitis is associated with increased oxidative stress and epigenetic alterations

11:45 - 13:15


Huey Tan

UK

Antioxidant supplementation alters immune cell phenotype and function in alcoholic hepatitis

11:45 - 13:15


Kristen Lilly

UK

Outcome of hospitalisation in alcohol related liver disease compared to other aetiologies of liver disease in secondary care population: a UK multicentre study

11:45 - 13:15


Abhishek Sheth

UK

Cyclophilin inhibitor rencofilstat as a potential therapy for alcohol-related liver disease

11:45 - 13:15


Una Rastovic

UK

Closing Ceremony

Room A

Local Time: 13:15 - 14:00 CEST (GMT+2 Warsaw)

Your time ZONE: -

Feel free to ask any questions

Organizers:

ISBRA – International Society for Biomedical Research on Alcoholism

ESBRA – European Society for Biomedical Research on Alcoholism

Conference Office:

Polish Travel Quo Vadis Sp. z o.o.

Ptasia 2, 00-138 Warsaw, Poland